EORTC has successfully conducted clinical research in ovarian, cervical, uterine and vulvar cancer for decades. Many of these trials were unique and changed clinical practice. Today, the Group is focused on molecular approaches to patient management. Their aim is to discover clinically-useful predictive factors to identify subgroups of patients based on genomic patterns and activated pathways, and tailor clinical trials to them. The Group also stimulates clinical trials in rare cancers and underserved populations within the gynecological field.