Head & Neck Group
EORTC 24891 – Is laryngeal preservation with induction chemotherapy safe in the treatment of hypopharyngeal squamous cell carcinoma?
A randomized phase III trial.
This landmark EORTC study found that larynx preservation treatment does not jeopardize overall survival in patients with squamous cell cancer of the head and neck. The results of this study changed standard of care and practice from larynx surgery to larynx-preserving radio-chemotherapy treatment, preserving natural speech and quality of life for these patients.