May-97 -

Radiation Oncology Group

EORTC 22861 – Randomized phase II-III trial of radiotherapy alone or with concomitant chemotherapy in the treatment of anal carcinoma.

Joint study of the EORTC Gastrointestinal Tract Cancer Group (GI Group) and the EORTC Radiotherapy Cooperative Group.

EORTC found that combining a chemotherapy treatment of fluorouracil (5FU)–mitomycin-C (MMC), and radiotherapy improved locoregional control and spared colostomy in patients with locally advanced anal cancer.

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