Radiation Oncology Group
EORTC 22953 – Shortened irradiation scheme, continuous 5FU and fractionation of Mitomycin C in locally advanced anal carcinoma.
Joint study of the EORTC Radiotherapy Cooperative Group and the EORTC Gastrointestinal Tract Cancer Cooperative Group.
EORTC found that in patients with locally advanced anal cancer, reducing gaps between radiotherapy sequences, delivering chemotherapy during the course of radiotherapy, and reducing irradiation, improved local control the cancer and overall survival of patients, while sparing them colostomy. This new treatment scheme has been considered the new standard of treatment for this type of cancer.