Lung cancer Group
EORTC 22993/08993 – Prophylactic cranial irradiation in extensive disease small cell lung cancer.
A joint study with the EORTC Radiotherapy and Lung Cancer Groups
EORTC’s study on prophylactic cranial irradiation (PCI) has been internationally adopted as the standard of treatment in patients with small cell lung cancer. It found that prophylactic cranial irradiation (PCI) reduces the risk of symptomatic brain metastases and improved survival in patients with advanced-disease in small cell lung cancer, without significant difference in cognitive and emotional functioning.