Jul-09 -

Gastro-Intestinal Group

EORTC 40993 – International phase III open label randomized trial comparing CPT-11 in combination with high dose 5FU/Folinic acid infusional regimen (group A) to the same high dose 5FU/Folinic acid infusional regimen (group B) alone as adjuvant treatment stage III colon cancer (PETACC-3).

This EORTC study results showed the absence of benefit in adding irinotecan to 5FU treatment, in the adjuvant setting of stage III colon cancer.

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