Collection of Studies
Between 1963 and 1974, the EORTC Breast Cancer Group (BCG) conducted a number of studies that led to practice changing development in hormone therapy in patients with breast cancer. The group was the first to demonstrate how nafoxidine stops pre-cancerous growths in postmenopausal women. By 1974, the EORTC BCG tested a combination treatment of tamoxifen and two alternating chemotherapies (AV and CMF). The results demonstrated that this treatment led to higher response rates and complete remission rates, stimulating more research into treating breast cancer with combined endocrine and chemotherapy.